Acrochordon

  • Aka Skin Tags

Definition

  • Commonly known as skin tags or fibroepithelial polyps, are benign outgrowths of normal skin

Risk factors

  • Acrochordons are common in adult individuals,
  • Risk increases with age
  • Obesity
  • Diabetes mellitus
    • Observational studies suggest that acrochordons may be a skin sign of insulin resistance and metabolic syndrome
  • Skin tags also appear with increased frequency during the second trimester of рrеgոаոϲу and may regress postpartum

Cause

  • Acrochordons usually occur in sites of friction
    • Axilla, neck, inframammary, and inguinal regions.

Clinical

  • They can become symptomatic and bothersome for many patients when traumatized (eg, caught on jewelry, rubbed by clothing, itching).
  • An infarcted аϲrοϲhοrԁοn, resulting from torsion of its peduncle, appears as a red or black lesion

Diagnosis

  • Clinical

Treatment

  • If irritating
  • Cosmetic

Dermatofibroma

Aka Histiocytoma

Definition

  • Common benign cutaneous neoplasm
  • Fibroblasts of the dermis forming a nodule under the epidermis

Incidence

  • Relatively common, F > M (4:1)
  • Usually occurs in young adults / 20s

Aetiology

  • Unknown, may have a genetic component

Clinical

  • Mostly on extremities (mostly lower legs)
  • Usually asymptomatic
  • May have pruritus/tenderness
  • 0.5-1cm hard nodule overlying skin can be many colours
  • Nodule may feel like a frozen pea or a small pebble fixed to skin surface, freely mobile over subcutaneous tissue
  • Characteristic tethering of the overlying epidermis with manual lateral compression of the skin = Dimple Sign
  • Most are solitary
  • Multiple seen in
    • SLE, HIV, Leukaemia

Pathology

  • Clonal cell growth
  • Proliferation of fibroblasts ? reactive ? neoplastic
  • Histology: Tumour is in the mid-dermis: Whirling fascicles of Spindle Cells
  • (DDx: Dermatofibrosarcoma Protuberans)

Investigations

  • Excision Bx if suspicious / atypical

Management

  • Removal of the tumour is not necessary, unless diagnostic uncertainty exists or troubling Sx are present – excised with subcutaneous tissue

Prognosis / Natural Hx:

  • Slow growth
  • Most lesions remain static indefinitely

Cutaneous neurofibroma

  • Cutaneous ոеսrofibrоma is a benign nerve sheath tumor composed of cells of neuromesenchymal origin, including Schwann cells, fibroblasts, perineurial cells, and mast cells.