Magnesium citrate is an osmotic laxative commonly used for bowel cleansing and treatment of constipation. Here’s a detailed breakdown:

  • Mechanism of action:
    • Magnesium citrate is a saline laxative → draws water into the intestinal lumen by osmotic effect
    • Increases intraluminal volume → stimulates stretch receptors in the intestinal wall → promotes peristalsis and bowel evacuation
  • Onset of action:
    • Oral: 0.5 to 6 hours (depending on dose and individual response)