- Heart Tube – formed from 2 vessels fusing together; develops muscle fibres in its wall and becomes pulsatile
- Differentiates into 4 parts. In cephalocaudal direction:
- Bulb
- Upper part becomes the Truncus Arteriosus – divides to become the Aorta and Pulmonary Trunk
- Lower part becomes most of the Right Ventricle
- Ventricle
- Forms most of the Left Ventricle
- Atrium
- Sinus Venosus
- Becomes mostly absorbed into the Right Atrium
- Tube grows faster than the primitive pericardial cavity – it thus bends such that:
- Bulb and Ventricle are in front of the Atrium and Sinus Venosus
- Bulb twists to the right and Ventricle to the left
