Definition

  • Nutcracker phenomenon
    • Refers to compression of the left renal vein
    • Most commonly between the aorta and the superior mesenteric artery
    • Leading to impaired blood outflow often accompanied by distention of the distal portion of the vein
  • Nutcracker syndrome
    • Clinical equivalent of nutcracker phenomenon characterized by a complex of symptoms with substantial variations

Incidence

  • Higher in female

Clinical features

  • Variable from asymptomatic microhematuria to severe pelvic congestion
  • Symptoms are often aggravated by physical activity
  • Hematuria
  • Pain or gonadal vein syndrome
  • Varicocele (left)
  • Orthostatic proteinuria
  • Orthostatic intolerance

Anatomy

  • Left renal vein is 6 to 10 cm in length
    • Unlike the right renal vein, receives tributaries of the left adrenal, left gonadal, ureteral, and communicating second (and occasionally third) lumbar veins before joining the IVC.
    • These tributaries have valves preventing reflux of the blood. In NCP, when the valves are absent or incompetent, the tributaries may decompress the LRV.
    • In contrast, the presence of competent valves in NCP may contribute to an increase in renal pressure and resultant formation of varices and collaterals. T

Diagnosis

  • CT
  • MRA
  • Angiography
  • USS

Management

  • Conservative
  • Surgical approaches
    • Medial nephropexy with excision of renal varicosities,
    • LRV bypass
    • LRV transposition with or without Dacron wedge insertion between SMA and aorta
    • SMA transposition
    • Renal-to-IVC shunt
    • Renal autotransplant
    • Gonadocaval bypass
    • Nephrectomy
  • Endovascular
    • Stenting