- Early
- Lethargy
- Weakness
- Irritability
- Weight loss
- Vague myalgias and arthralgias
- Late
- Follicular hyperkeratosis
- Coiled hair
- Perifollicular haemorrhages
- Poor wound healing
- May develop femoral neuropathy, leg oedema, and painful joint effusion
- Could measure plasma ascorbic acid levels
- Treatment: Standard multivitamins BID should be enough
