Carney triad

• Rare
  • Fewer than 100 cases are reported
  • Affects predominantly young females
  • No genetic link
  • Generally considered to be a nonhereditary disorder caused by a postzygotic somatic mosaicism epigenetic silencing of the SDHC promoter; this leads to a deficiency of the SDHx enzyme complex
• Associated with
  • GIST
  • Paragangliomas
  • Pulmonary chondroma
• Should be distinguished from the [[Carney-Stratakis dyad]
  • GIST
  • Paragangliomas