• Hypertensive lower oesophageal sphincter
  • “Oesophagogastric outflow obstruction” in Chicago classification

Defintion

  • Elevated basal pressure of LOS
    • Poor relaxation
    • Normal peristalsis in the oesophagus differentiates this from achalasia
  • Clinical:
    • Chest pain
    • Dysphagia
      • Caused by lack of compliance of the sphincter
  • Causes
    • idiopathic
    • secondary
      • structural or medication-related
  • 50% of these pts have an associated motility disorder of the oesophageal body
  • Investigations - as for achalasia
  • Manometry:
    • ↑ LES pressure (≥ 26mmHg), relaxation incomplete (but not always)
    • Normal peristalsis in oesophageal body
  • Management
    • Conservative
      • Three-quarters of patients experiencing spontaneous resolution of symptoms over 6 months.
      • Mild symptoms
        • It is reasonable to observe and consider treatment if symptoms persist.
    • Moderate-severe symptoms
      • As for achalasia, botox, balloon dilation
      • Myotomy indicated in pts not responding to medical Rx or dilation
        • Lap modified Hellers myotomy (+ Dor fundoplication if normal motility)