Classification
- Based on thier hemolytic properities
- Alpha
- Causes oxidation of iron within red blood cells
- Beta
- Causes lysis of red blood cells
- Further classified into Lancefield grouping
- Gamma
- No heamolysis
- Alpha
Alpha
- In alpha hemolysis, the red blood cells remain intact, but the hemoglobin is converted to biliverdin. This causes dark greening of the blood agar plate around the colonies.
- Pneumococci
S. pneumoniae: Causes bacterial pneumonia, otitis media and meningitis.
Beta
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Beta hemolysis is a complete hemolysis of erythrocytes by the enzyme hemolysin.
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Clear zones will appear around the colonies on the blood agar plate.
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Beta-hemolytic Streptococci are further divided into serological groups using specific antibodies that recognize surface carbohydrate antigens
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Group A Streptococcus S. pyogenes: Causes infections like strep throat, acute rheumatic fever, scarlet fever, acute glomerulonephritis and necrotizing fasciitis. Other Streptococci species may also possess the Group A antigen but are not human pathogens. These include S. dysgalactiae subsp. equisimilis and S. anginosus strains.
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Group B Streptococcus S. agalactiae: Causes meningitis in neonates and the elderly. Occasionally colonizing the female reproductive tract, they increase the risk for premature rupture of membranes and transmission of the infection to the child.
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Group C Streptococcus S. equi: Causes strangles infection in horses.
S. zooepidemicus: Causes infections in cattle, horses and other mammals. -
Group D Streptococcus (Enterococci)
Many former Group D Streptococci have been reclassified to the genus Enterococcus (e.g. S. faecalis, S. faciem, S. durans, S avium).
S. bovis and S. suis: Still in the Group D streptococci.
Gamma
- Gamma hemolysis is a misnomer as there is actually no hemolysis. Non-hemolytic or gamma-hemolytic Streptococci rarely cause disease.