• Sclerosis occurring in men and pre-menopausal women with longstanding T1DM
    • Often associated with other diabetic complications (retinopathy)
  • Clinical
    • One or more hard masses
    • Features often indistinguishable from malignancy
  • Aetiology
    • Likely immune reaction to abnormal accumulation of altered extracellular matrix
    • As a result of hyperglycaemia
  • Path
    • Sclerosing lymphocytic lobulitis
  • Natural hx
    • Doesn’t predispose cancer or lymphoma