Section: Breast Curriculum: Curriculum, page 9 and Curriculum, page 9
Relevant Breast anatomy
- Lobules/ducts
- Epithelial layer
- Myoepithelial (basal) layer
- Basement membrane
- Fibroepithelial/stromal tissue
| Non-proliferative | Proliferative | Proliferative with atypia | |
|---|---|---|---|
| RR | 1.2-1.4x | 1.7-2.1x | 4-5x |
| Epithelial | Mild ductal hyperplasia | Florid ductal hyperplasia | Atypical ductal hyperplasia |
| Fibroepithlial lesion | Fibroadenoma | Pseudoangiomatous Stromal Hyperplasia (PASH) | Complex fibroadenoma |
| Metaplasia (cuboid to columnar) | Simple columnar alteration | Columnar hyperplasia | Flat epithelial atypia (RR 1.5x) |
| Sclerosing lesion | Sclerosing adenosis | ||
| Radial Scar and Complex Sclerosing Lesion | |||
| Lobular | Likely starts from epithelial cells | Atypical lobular hyperplasia | |
| Lobular carcinoma in situ | |||
| Papilloma | Papilloma without atypia | Papilloma with atypia |
- Congenital abnormalities of the breast
- Aberrations of Normal Breast Development and Involution (ANDI)
- Fibrosis
- Cystosis
- Adenosis
- Epithelial hyperplasia