A specialised assay specifically designed to measure dabigatran levels.
| Dilute TCT (sec) | Possible Interpretation |
|---|---|
| < 35 sec (Normal) | No significant thrombin inhibitor or fibrinogen abnormality |
| 35–50 sec (Mild prolongation) | Low-level direct thrombin inhibitor (e.g., low-dose dabigatran) OR mild fibrinogen abnormality |
| > 50 sec (Markedly prolonged) | High levels of dabigatran or another DTI |
| > 100 sec (Very prolonged) | Strong direct thrombin inhibition (e.g., therapeutic dabigatran levels) OR severe fibrinogen disorder |
| Prolonged dTCT with normal reptilase time | Suggests dabigatran or another thrombin inhibitor |
| Prolonged dTCT with prolonged reptilase time | Suggests hypofibrinogenemia/dysfibrinogenemia (e.g., liver disease, DIC) |