Section: Critical care Curriculum: Curriculum, page 47

General

  • M>F
  • Age 50
  • Bilateral uncommon
  • Anatomy of Psoas Major
    • Origin: Disc of T12-L5 vertebrae
    • Inserts: Lesser Trochanter of Femur
    • Crossed pelvic brim and deep to inguinal lig
    • Anterior to hip joint capsule (separated by iliopsoas bursa)
    • Nearby structure where infection can spread
      • AA
      • Vertebral Body
      • Sigmoid and appx
      • Hip joint
      • Iliac LN

Classification

  • Primary (haematogenous/lymphatic) vs secondary (direct)
    • Primary (haematogenous/lymphatic seeding from distant site)
      • Risk Factors
        • Immunosuppression
        • DM
        • IVDU
        • HIV
        • Renal failure
        • Septic emboli
        • Cardiac origin infective endocarditis
    • Secondary (direct)
      • Risk Factors
        • Trauma
        • Local instrumentation
        • Local structures
          • Vertebral Body
            • Osteomyelitis
          • Hip joint capsule
            • Post arthroplasty
          • GIT
            • All cause colitis
            • Appendicitis
            • Diverticulitis
          • Mycotic aortic aneurysm
          • Complication from renal surgery
          • GUT
            • PID, TOA, UTI, pyelo
          • MSK
            • Septic joint hip, osteomyelitis, discitis, potts disease (TB)

Pathology/Micro

  • Primary
    • Single organism
    • Most common = staph aureus (including MRSA)
    • In countries where TB is common, mycobacterium tuberculosis
  • Secondary (dependent on pathology)
    • Likely enteric organisms
    • Monomicrobial
    • Polymicrobial
    • Tuberculosis of the spine is an important cause of retroperitoneal abscesses in immunocompromised individuals and in those immigrating from underdeveloped countries.

Clinical

  • Symptoms - weeks to months
  • Could present shocked
  • Local
    • Back/flank pain +/- radiation to hip
    • Inguinal mass
      • If not tender and below inguinal lig - cold mass could be TB
    • Limping
  • Systemic
    • Fever
    • Anorexia
    • Weight loss
  • Signs
    • Psoas sign positive - hip extension
    • POSITION OF COMFORT - HIP FLEXED, LUMBAR LORDOSIS

Complications

  • Local
    • Hydronephrosis
    • Ileus
    • Septic arthritis of hip
    • DVT
  • Systemic
    • Shock

Investigations

  • Bloods
    • WBC, CRP
    • Culture Blood culture for haematogenous spread
    • Quantiferon gold
  • Aspirate
    • TB - AFB gram staining
  • Biopsy
    • ?suspicion for malignancy
  • Imaging
    • CT abdo pelvis - ID hypodense ?loculated area in psoas muscle and concurrent abdominal pathology
    • MRI if suspicious for joint or spinal involvement

Differential diagnosis

  • Haematoma
  • Retrocaecal appendicitis
  • Bursitis
  • Septic hip arthritis

Management

  • Principles
    • Source control - drainage, abx
    • If secondary, treat underlying cause
  • Antibiotics
    • Emperic
      • Suggest cover for
        • Staph Aureus (+/- to cover MRSA
          • Cefazolin or Cefalexin
          • Or for MRSA - Vancomycin, co-trimoxazole, Clindamycin
        • Cover enteric bugs
          • Cefuroxime and Metronidazole, Tazocin, Meropenum
    • Then guided by cultures
    • Duration dependent on situation but likely prolonged course e.g. 4 weeks
  • Radiological
    • Percutaneous drain placement - CT guided
    • Failed abx management (most won’t settle alone), large abscess
  • Surgical
    • Laparoscopic vs open
    • Indications complex abscess failed drainage and abx
      • Multiloculated
      • Significant local involvement needing surgical intervention
        • E.g bowel pathology IBD
    • Open drainage • McBurney incision • Muscle splitting • Extraperitoneal plane developed • Peritoneum pushed medially • Identify psoas muscle: medial posterior abdominal wall • Aspirate muscle with 18G needle. • Incise to drain pus • Place large closed suction drain, through separate skin incision • Close wound in layers

Prognosis

  • 20% - septic shock
  • Recurrence or poor prognosis related to
    • Disease Factors
      • E.coli
      • Bacteraemia
      • Inadequate drainage
    • Patient Factors
      • Advanced age
      • CV disease
      • Immunosuppression