Serrated polyps of the appendix, with or without dysplasia, resemble the serrated lesions of the colon but have differing molecular features. In the past, serrated lesions lacking dysplasia have been called “hyperplastic polyps” of the appendix if focal and “mucosal hyperplasia” if flat and circumferential or otherwise diffuse. Typically, serrated polyps of the appendix are not associated with fibrosis or thickening of the appendiceal wall or loss of the lamina propria.