Section: Hepatobiliary Sub-section: Biliary Curriculum: Curriculum, page 89

  • Adenomyomatosis of the gallbladder is a hyperplastic cholecystosis of the gallbladder wall.
    • Characterized by overgrowth of the mucosa, thickening of the muscle wall, and intramural diverticula.
  • It is a relatively common and benign cause of diffuse or focal gallbladder wall thickening, most easily seen on ultrasound and MRI.
  • Hyperplasia of the wall with the formation of Rokitansky-Aschoff sinuses (intramural diverticula lined by mucosal epithelium) penetrating into the muscular wall of the gallbladder, with or without gallbladder wall thickening.

Management

  • Patient symptomatic with right upper quadrant pain (often due to gallstones)
  • Appearances (especially when focal) may be difficult to distinguish from malignancy
  • Simple adenomyomatosis is not a premalignant condition.
  • In absence of symptoms, no treatment.