• Sarcoma
  • Arise from endothelial cells
  • Include
    • Scalp in older adults
    • Breast or chest wall after therapeutic radiation for breast ϲanϲеr
    • An extremity in conjunction with chronic lymphedema Stewart-Treves Syndrome
    • Deep soft tissues
    • Liver or spleen
    • Heart or large vessels.
  • Usually high grade and not responsive to treatment.
  • Is commonly caused by therapeutic radiation - especially for breast cancer or Hodgkin lymphoma