• Congenital anomalies, arising in early embryonic development
    • Most commonly small intestine
    • Can be oesophagus, stomach, colon
    • Oesophagus seen in 1:8000 live births
  • 3 criteria
    • Lay in wall of oesophagus
    • Covered by two muscle layers
    • Contain squamous epithelium
      • Or lining compatible with tissue found in oesophagus
  • Up to 1/3 contain heterotrophic gastric mucosa
    • Can also have pancreatic mucosa or mucosa consistent with Peyer’s Patches
  • 80% do not communicate with oesophageal lumen
    • Others run in parallel and do communicate
  • Most commonly on the right lateral portion of oesophagus
  • Frequently cause symptoms (unlike in other parts of the GI tract)
    • Because of this, most diagnosed before the age of 2
    • Symptoms from compression
      • Dysphagia
      • Epigastric or retrosternal pain
      • Respiratory symptoms (cough, stridor, wheeze)
  • Surgically resect symptomatic cysts
  • Malignancy rare but has been reported

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