- G20210A mutation in the Prothrombin (Factor II) gene
- Second most common
- Variant is a point mutation in which adenine is substituted for guanine at position 20210 in F2 gene
- Mechanism incompletely understood
- Though secondary to increased concentration ad possibility efficiency of prothrombin
- Diagnosis
- Treatment similar to Factor V Leiden
- Asymptomatic - nil
- Symptomatic - as per normal Deep vein thrombosis.
- Individualize the duration of аոtiϲοаgսlаtion according to features such as whether the VΤЕ was provoked, life-threatening, or at an unusual site, as done for the general population, rather than a more aggressive approach.