- GnRH Analogues (LHRH Agonists)
- Suppress the production of oestrogen (chemical ovarian ablation)
- Stimulates production of oestrogen/testosterone in a non-pulsatile manner
- Disruption of feedback system resulting in overall down regulation of testosterone and oestrogen
- NB: Initial increase in production but after ~ 14-21 days there is a significant reduction in LH release