Background for development of atypical epithelial proliferations including ADH (Atypical Ductal Hyperplasia) and DCIS
Increased risk of malignancy
Difficult to distinguish from malignancy – associated with malignancy ~ 10%
Open excision recommended
Management
Traditionally radial scar and complex sclerosing lesion were surgical excised always
Based on series showing that 8 to 17 percent of surgical specimens at subsequent excision are positive for malignancy
Contemporary series suggest the presence of undiagnosed cancer is much lower, with upgrade rates in the range of 0.6 to 3.6 percent
American Society of Breast Surgeons state
“Should be excised”
Although imaging follow-up is reasonable for small, image-detected radial scars that are completely removed or well-sampled with large-gauge devices and in the setting of imaging-pathology concordance