• Inject beneath the lesion to lift it and separate it from the muscularis propria.
    • Use a needle to inject a solution, typically saline or a mixture with epinephrine (to reduce bleeding) and a dye like methylene blue or indigo carmine (to visualize the lift).
    • Ensure an adequate and uniform submucosal cushion is created (“the lift”).
  • Resection
    • Snaring:
      • Use a snare to encircle the lesion.
      • Position the snare around the elevated lesion and close it gently to capture the base of the lesion.
    • Electrocautery:
      • Apply electrocautery energy to cut and cauterize simultaneously. Settings depend on lesion location and equipment.
      • Resect in piecemeal fashion for larger lesions (piecemeal EMR) or en bloc for smaller lesions.