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Oesophagus

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Alkylating agents

Alkylating agents

Chemotherapy

  • Antiproligerative

  • Bind via alkyl groups to DNA

  • Arrest cell cycle in the G1/S phase

  • Oxaliplatin

    • FOLFOX, CAPOX, FOLFIRI, FOLFIRINOX, FOLFOXIRI
      • Colorectal cancer, Gastric adenocarcinoma
    • FLOT4 for Gastric adenocarcinoma and Oesophageal cancer
  • Carboplatin

    • CROSS Trial for Oesophageal cancer
  • Cisplatin

    • MAGIC Trial for Gastric adenocarcinoma and Oesophageal cancer
      • ECF and ECX
  • Cyclophosphamide

    • Early-stage breast cancer
  • Streptozocin

Side effects

  • Nausea & vomiting
  • Alopecia
  • Myelosuppression

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Backlinks

  • Adjuvant Therapy for breast cancer
  • Early-stage breast cancer
  • Cytostatics
  • Chemotherapy
  • Oxaliplatin
  • Carboplatin
  • Cyclophosphamide
  • Oesophagus

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